Selection of Syndromes and Algorithms for Monitoring Bovine Laboratory Test Data

The Johns Hopkins University Applied Physics Laboratory is collaborating with epidemiologists of the US Dept. of Agriculture's Animal and Plant Health Inspection Service (APHIS) Center for Epidemiology and Animal Health (CEAH) to increase animal health surveillance capacity. CEAH monitors selected syndromic animal health indicators for stakeholder reporting. This project’s goal was to extend this capacity to bovine veterinary laboratory test accession data.


January 19, 2018

Surveillance of Human Papilloma Virus in the United States to Evaluate Vaccine Impact

Numerous studies have demonstrated a causal relationship between human papillomavirus (HPV) and cervical cancer1. By 2007 two vaccines targeting HPV were available in the United States. Both vaccines have shown close to 100% efficacy against HPV types 16 and 18, the cause of 70% of all cervical cancers2. It is hypothesized that with routine vaccination the prevalence of HPV and HPV-associated cancers should decline3. A need exists for surveillance with national coverage2.

May 02, 2019

The Evolution of the WHO/NREVSS Influenza Surveillance System: The Challenges and Opportunities that Accompany Electronic Laboratory Data

The Influenza Division (ID) in the Centers for Disease Control and Prevention (CDC) maintains the WHO/NREVSS surveillance system, a network of laboratories in the U.S. that report influenza testing results. This system has seen many changes during the past 40 years, especially since the 2009 H1N1 pandemic. This was due in large part to increased adoption of HL7 messaging via PHLIP. PHLIP data is detailed, standardized influenza testing information, reported in near real-time.

May 02, 2019

Under-ascertainment of Illness due to Influenza in Administrative Databases, a Population-based Record Linkage Study

Under-ascertainment of severe outcomes of influenza infections in administrative databases has long been recognised. After reviewing registered deaths following an influenza epidemic in 1847, William Farr, of the Registrar-General's Office, London, England, commented: ''the epidemic carried off more than 5,000 souls over and above the mortality of the season, the deaths referred to that cause [influenza] are only 1,157"[1].

May 02, 2019

Use of Laboratory Drug Sensitivity Tests and Prescription Practices in Malawi

Of the 13 million people in Malawi1 85% are rural and the country has high burden of under-five morbidity and mortality due to preventable infectious diseases. Respiratory, febrile and diarrhea diseases are the top 3 morbidity and mortality illnesses in most developing countries2. Acute medical care has greatly improved these conditions, but widespread and uncontrolled use of antibiotics threatens to reverse gains achieved so far. Drug sensitivity tests are a prerequisite to guide prescription practices.


May 02, 2019

Comparison of respiratory, febrile and influenza-like illness syndromes to detect laboratory-reported H1N1 and RSV, Influenza Season 2009–10, New York City

The New York City (NYC) Department of Health and Mental Hygiene monitors visits daily from 49 of 54 NYC emergency departments (EDs), capturing 95% of all ED visits. ED visits for influenza-like illness (ILI) have reflected influenza activity in NYC, better than the more broadly defined fever/flu and respiratory syndromes, but the correlation with H1N1 is unknown. 

Laboratory-confirmed influenza and respiratory syncytial virus (RSV) were made reportable in NYC in February 2008. DOHMH receives electronic reports of positive tests. 

June 14, 2019

Evaluation of Microbiology Orders from a Veterinary Diagnostic Laboratory as a Potential Data Source for Early Outbreak Detection

Animals continue to be recognized as a potential source of surveillance data for detecting emerging infectious diseases, bioterrorism preparedness, pandemic influenza preparedness, and detection of other zoonotic diseases. Detection of disease outbreaks in animals remains mostly dependent upon systems that are disease specific and not very timely. Most zoonotic disease outbreaks are detected only after they have spread to humans. The use of syndromic surveillance methods (outbreak surveillance using pre-diagnostic data) in animals is a possible solution to these limitations.

July 30, 2018

Age Specific Correlations between Influenza Laboratory Data and Influenza-like Syndrome Definitions in Boston and New York City

To compare age-group-specific correlation of influenza-like syndrome (ILS) emergency department (ED) visits with influenza laboratory data in Boston and NYC using locally defined ILS definitions.

July 30, 2018

Web-Based Spatio-Temporal Display of NC DETECT Surveillance Data

NC DETECT is the Web-based early event detection and timely public health surveillance system in the North Carolina Public Health Information Network. The reporting system also provides broader public health surveillance reports for emergency department visits related to hurricanes, injuries, asthma,  vaccine-preventable diseases, environmental health and others.

July 30, 2018

Detection of Shigella Outbreaks in Argentina Using WHONET and SaTScan

Electronic laboratory-based surveillance can significantly improve the diagnostic specificity and response time of traditional infectious disease surveillance. Under the project “Models of Infectious Disease Agent Study”, we wished to evaluate the application of space-time outbreak detection algorithms utilizing SaTScan to a national database of routinely collected microbiology laboratory data.



July 30, 2018


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