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Click on a topic under the Key Topic Areas section in the left column, then select a resource  from the list of resources that appear for that topic. You may also search for specific topics by entering one or more keywords in the Search bar. You can filter the search results by Content Type, Year, or Author Name.


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Per a frequently asked questions document on the ISDS website, approximately two thirds of HL7 records received in BioSense do not provide a Visit ID. As a result, BioSense data processing rules use the patient ID, facility ID and earliest date in the record to identify a unique visit. If the... Read more

Content type: Abstract

Michigan has been collecting chief complaint data from emergency departments statewide to support situational awareness activities related to communicable disease since 2004. We validated the syndromic system by comparing the chief complaint data to the electronic medical records of a tertiary... Read more

Content type: Abstract

Cholera causes frequent outbreaks in Nigeria, resulting in mortality. In 2010 and 2011, 41,936 cases (case fatality rate [CFR]-4.1%) and 23,366 cases (CFR-3.2%) were reported (1). Reported cases in Nigeria by week 26, 2012 was 309 (CFR-1.29%) involving 20 Local Government Areas in 6 States. In... Read more

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Public health disease surveillance is defined as the ongoing systematic collection, analysis and interpretation of health data for use in the planning, implementation and evaluation of public health, with the overarching goal of providing information to government and the public to improve... Read more

Content type: Abstract

The utility of syndromic surveillance systems to augment health departments’ traditional surveillance for naturally occurring disease has not been prospectively evaluated.



In this interim report we describe the signals detected by a real-time ambulatory care-... Read more

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The Miami-Dade County Health Department currently utilizes Emergency Department based Syndromic surveillance data, 911 Call Center data, and more recently Public School Absenteeism data. Daily monitoring of school absenteeism data may enhance early outbreak detection in Miami-Dade County in... Read more

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Cardiothoracic surgery quality improvement is a core value of healthcare provision. In order to improve quality of care, information on key indicators needs to be systematically collected and maintained.In 2006, thecardiothoracic department at AgaKhan University developed an infrastructure that... Read more

Content type: Abstract

Since 2015, CDC’s Division of Health Informatics and Surveillance staff have conducted evaluations to provide information on the utility, functionality, usability and user satisfaction associated with the National Syndromic Surveillance Program’s BioSense Platform tools. The BioSense... Read more

Content type: Abstract

With economic pressures to shift the care of community-acquired pneumonia (CAP) to the ambulatory setting, there is a need to ensure safety of outpatients with CAP. The use of claims data alone remains the primary strategy for identifying these patients, but billing information often does not... Read more

Content type: Abstract

An objective of the Joint VA/DoD BioSurveillance System for Emerging Biological Threats project is to improve situational awareness of the health of combined VA and DoD populations. DoD and VA both use versions of the Electronic Surveillance System for the Early Notification of Community-Based... Read more

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National Syndromic
Surveillance Program


The National Syndromic Surveillance Program (NSSP) is a collaboration among states and public health jurisdictions that contribute data to the BioSense Platform, public health practitioners who use local syndromic surveillance systems, Center for Disease Control and Prevention programs, other federal agencies, partner organizations, hospitals, healthcare professionals, and academic institutions.

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